China (Mainland)
3-Deoxy 3-chloroabiraterone with high purity in stock
- FOB Price: USD: /Gram Get Latest Price
- Min.Order: 10 Milligram
- Payment Terms: T/T
- Available Specifications:
purity>98%(0-1)Gram
- Product Details
Keywords
- 3-Deoxy 3-chloroabiraterone
- abiraterone
- abiraterone impurity
Quick Details
- ProName: 3-Deoxy 3-chloroabiraterone with high ...
- Molecular Formula: C24H30ClN
- Appearance: Off-White Solid
- Application: For lab research use only
- DeliveryTime: Package will dispatched in 7-15 days(A...
- PackAge: Moisture-proof packing
- Port: Shenzhen
- ProductionCapacity: Metric Ton/Day
- Purity: >98%
- Storage: Store at 2-8℃, dry, in dark
- Transportation: by air
- LimitNum: 10 Milligram
Superiority
Topbatt Chemical Co., Ltd., Established in 2019, located in Shenzhen, Guangdong Province, is a Manufacturer and Trading company which specialized in fine chemicals like Pharmaceutical Reference Standards and Stable Isotopes. Our Stable Isotopes product line including 2H Labelled APIs, Reagents and Intermediates, 13C Labelled Substance, 15N Labelled Substance and 18O Labelled Substance.
We own a number of Senior pharmaceutical synthetic engineer, analysis engineer and analytical testing instrument. It make us have more than 1700 varieties compouds with high purity in stock in a short time.
We can provide you not only stock items, but also Custom Synthesis Service.
All of our products provided with COA, HPLC/GC, HNMR, qNMR, MS Spectrum.
Contact us at 0086-18923794376 or email us at yehh@topbatt.net, 24/7 stand by for you.
After-sales issues will be settled in 24 hours.
Details
Product Name: 3-Deoxy 3-chloroabiraterone
Chemical Name: 3-((3S,8R,9S,10R,13S,14S)-3-chloro-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine
Molecular Formula: C24H30ClN
Molecular Weight: 367.96
CAS#: N/A
Purity: >98%
Appearence: Off-White Solid
Price: Negotiable
Available Document: COA, HPLC/GC, HNMR, qNMR, MS Spectrum
Payment Term: Payment in advance by T/T.
Shipment: Package will dispatched in 7-15 days(According to the date of payment) by air.
Trade Term: EXW, FOB, CFR, DDU, DDP, ect.
3-Deoxy 3-chloroabiraterone is an impurity of Abiraterone. Abiraterone acetate is the 3β-acetate form of its active component abiraterone, a potent inhibitor of androgen biosynthesis. Abiraterone, a pregnenolone-derived 3-pyridyl steroidal compound, potently and irreversibly inhibits cytochrome P450 17 alpha-hydroxylase (CYP17), an important enzyme involved in the synthesis of androgen and cortisol, through a covalent binding mechanism with a value of 50% inhibition concentration IC50 of 72 nM, which is 10 to 30 times greater in potency, due to the 3-pyridyl substitution in its chemical structure, than the inhibition by ketoconazole. In order to improve the low solubility of abirateone, abiraterone acetate has been developed and used for the treatment of castration-resistant prostate cancer (CRPC).
